ULCODERMA is a topical enzymatic ointment for debridement and wound healing in the treatment of post-traumatic and trophic dermal lesions, composed of Clostridiopeptidase A and chloramphenicol.
Each 100 g of ointment contains:
| Clostridiopeptidase A (Collagenase) | 60U |
| Chloramphenicol | 1g |
| Excipient cbp | 100g |
Benefits
- Stimulates and accelerates the healing process
- Prevents infection during the healing process.
- Cleans non-viable tissue from the wound.
Dosage and route of administration
- The route of administration is topical. ULCODERMA should be applied in a thin layer (2 mm) covering the entire surface of the lesion.
- Generally, one application per day is sufficient, but if medical criteria consider that a more intense effect is required due to the characteristics of the lesion, it can be applied twice a day. It is unnecessary to apply too large an amount of the product to the wound. With this, the cleaning process is not improved. An increase in activity may possibly be obtained by applying the ointment twice a day.
- In general, changing the bandage once a day will be sufficient. The treatment of varicose ulcers with collagenase ointment will be usefully complemented by a pressure bandage and for arterial circulation disorders, ulcers of diabetic or neurological etiology, by treatment with the appropriate medication.
- To ensure the success of enzymatic wound treatment with collagenase ointment, sufficient moisture must be present in the wound area during treatment. In dry wounds, the wound base should therefore be moistened with normal saline (0.9% NaCl) or other solutions that are well tolerated by the tissue (e.g. glucose). Dry, hard scabs should first be softened by applying a moist dressing.
- Collagenase treatment should be stopped when the entire wound surface is clean. When an infection is present, treatment with an appropriate antibiotic should be considered. Chloramphenicol, neomycin, framycetin, bacitracin, gentamicin, polymyxin B and macrolides, e.g. erythromycin, have been shown to be compatible with collagenase.
- As is common in clinical practice, the wound edges and healthy skin should be protected in order to avoid irritation.